Abstract
Acacia coacervated by gelatin, without any cross linking agent, was found to be an
excellent stabilizer for medicinal emulsions. The thickness and some properties of
interfacial films of gelatin-acacia mixture formed at oil-water interface have been
studied. Viscosity measurements and serial washing of the disperse phase have been
used. Gelatin-acacia coacewates stabilize oil-in-water emulsions by forming strong
interfacial films, although their mean film thickness is about the same thickness
as those of gelatin or acacia used separately. Because of the irreversible adsorption
of these macromolecules at the interface which forms a strong and relatively insoluble
coacervate film, stabilization of medicinal disperse systems by coacervation seems
to be of practical use.
